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  • Title: Experiments with micro-organisms and human cell cultures in the Zond 5 and Zond 7 flights.
    Author: Zhukov-Verezhnikov NN, Volkov MN, Maisky IN, Rybakov NI, Guberniev MA, Podoplelov II, Kulagin AN, Aniskin ED, Rybakova KD, Sharyi NI, Voronkova IP, Saxonov PP, Kopyev VY, Antipov VV, Kozlov VA, Parfyonov GP, Orlovsky VI.
    Journal: Life Sci Space Res; 1971; 9():99-103. PubMed ID: 11942358.
    Abstract:
    Lysogenic strains of Escherichia coli were exposed to space conditions aboard the flight of Zond 5 and Zond 7. Space flight factors appeared to affect the state of episome systems of bacteria, as judged by data obtained with F-Lac+ donor cells which also carried genetic markers for threonine and leucine. Observations on phage induction are discussed and compared with results obtained aboard Biosatellite 2. A number of monolayer cultures of human cells (HeLa cells, fibroblasts, and A-1 cells) were repeatedly exposed to the space environment. In one instance, HeLa 19 cells increased in size after exposure to space conditions, a change which appeared to be genetically stable. HeLa 19 cells which were carried on six separate space flights showed a higher viability than corresponding cultures which were exposed only once aboard Zond 5.
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