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  • Title: A nitric oxide-releasing polydiazeniumdiolate derived from acetonitrile.
    Author: Arnold EV, Citro ML, Keefer LK, Hrabie JA.
    Journal: Org Lett; 2002 Apr 18; 4(8):1323-5. PubMed ID: 11950353.
    Abstract:
    Acetonitrile, frequently used as a solvent in reactions of nitric oxide (NO) with amines and other nucleophiles to introduce the [N(O)NO](-) (diazeniumdiolate) functional group, has itself been shown to react with NO in the presence of strong base to yield methane trisdiazeniumdiolate (1), presumably via an intermediate trisdiazeniumdiolated imidate. Aqueous hydrolysis of 1 does not follow simple first-order kinetics and produces mixtures of NO and nitrous oxide in ratios that vary with solution pH. [reaction: see text]
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