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  • Title: [Retrospective analysis of misdiagnosed amoebic keratitis].
    Author: Li S, Xie L, Shi W, Wang J, Wen Y.
    Journal: Zhonghua Yan Ke Za Zhi; 2002 Jan; 38(1):21-3. PubMed ID: 11955295.
    Abstract:
    OBJECTIVE: To analyze the clinical characteristic of amoebic keratitis and the cause of misdiagnosis retrospectively. METHODS: Corneal pathological sections of 269 cases having been diagnosed as herpes simplex keratitis (HSK), bacterial keratitis and other microbial keratitis and then undergone penetrating keratoplasty (PKP) were reexamined to find the misdiagnosed cases of amoebic keratitis. The clinical characteristic efficacy of treatment and cause of misdiagnosis were retrospectively analyzed according to case history and photographs. RESULTS: Based on the pathological examination, 5 cases of amoebic keratitis were recognized which had been misdiagnosed, including HSK in 3 cases, fungal keratitis in 1 case and suppurative keratitis in 1 case previously. The main clinical characteristics were severe radiating neuralgia and ring-shaped stromal infiltrates. After PKP, infection of 3 cases were controlled, 2 cases were recurrent and underwent eyeball enucleation eventually. CONCLUSION: The incidence of amoebic keratitis is not very low in China. It is necessary to pay high attention to this kind of disease, and its early and definite diagnosis is very important for the prevention of serious results.
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