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  • Title: [Regan-isoenzyme of alkaline phosphatase in sera of cancer patients (author's transl)].
    Author: Lehmann FG.
    Journal: Klin Wochenschr; 1975 Jun 15; 53(12):585-7. PubMed ID: 1195659.
    Abstract:
    The Regan-Isoenzyme of alkaline phosphatase was determined immunologically measuring the antibody-fixed tumor alkaline phosphatase activity. In 68 blood donors the normal range varied from 0.1145 to 0.6351 (delta E/20 min at 405 nm, chi = 0.3748, standard deviation = 0.1013). 28.9% of 83 patients with different carcinomas showed a pathologically elevated Regan-Isoenzyme activity in the serum. The percentage of positive results as compared to previous reports is higher due to a more sensitive technique.
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