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  • Title: [Pancreas-preserving total duodenectomy due to familial adenomatous polyposis in 4 patients].
    Author: Konsten JL, Kazemier G, Dees J, van Eijck CH.
    Journal: Ned Tijdschr Geneeskd; 2002 Mar 30; 146(13):621-4. PubMed ID: 11957383.
    Abstract:
    In 4 patients with familial adenomatous polyposis (FAP) and multiple severe dysplastic adenomas in the duodenum (a 42-year-old woman and 3 men aged 44, 53 and 33 years, respectively), pancreas-preserving total duodenectomy (PPTD) was carried out. In 2 of the patients, serious early post-operative complications arose (leakage and haemorrhage of the gastrojejunostomy, respectively), and 1 patient developed a late complication (attacks of pancreatitis). During the 1-5-year follow-up period, small villous adenomas were seen in the jejunum (neoduodenum) of 1 of the patients. PPTD is a technically possible procedure which allows targeted treatment to be carried out if duodenum polyps are found upon endoscopic examination.
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