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  • Title: [Age variation of the phenotypic expression and the inheritance of the IgG system of immunoglobulin allotypes in the pig].
    Author: Nikitin SV, Savina MA, Kniazev SP, Gorelov IG, Bekenev VA, Iudina OP, Novikov AA, Ermolaev VI.
    Journal: Genetika; 2002 Mar; 38(3):368-75. PubMed ID: 11963565.
    Abstract:
    The specificity of phenotypic expression and inheritance of immunoglobulin allotypes IgG1a and IgG2b in pigs are discussed. It was shown that a negative state by both these allotypes is repeatedly found among newborn pigs but is extremely rare in pigs older than one month. A model, which simultaneously describes the genetic determination of allogroups formed by allotypes IgG1a and IgG2b and the dynamics of ontogenetic expression of individual genotype by system IgG with a result of a visually registered phenotype, was developed. Allele frequencies by system IgG were assessed in populations of domestic pigs of productive breeds, laboratory miniature pigs, and wild Eurasian pigs.
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