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  • Title: The bispectral index response to tracheal intubation is similar in normotensive and hypertensive patients.
    Author: Nakayama M, Ichinose H, Yamamoto S, Kanaya N, Namiki A.
    Journal: Can J Anaesth; 2002 May; 49(5):458-60. PubMed ID: 11983658.
    Abstract:
    PURPOSE: To compare the hemodynamic and bispectral index (BIS) responses to tracheal intubation in normotensive and hypertensive patients. METHOD: Three minutes after induction of anesthesia with thiamylal and fentanyl, tracheal intubation was performed in 24 normotensive and 22 hypertensive patients. Heart rate (HR), mean arterial pressure (MAP), and BIS were measured every minute. RESULTS: Tracheal intubation increased HR, MAP, and BIS in both normotensive and hypertensive patients. The increase in MAP was significantly greater in hypertensive patients than in normotensive patients, but there were no differences in HR or BIS in the two groups of patients. CONCLUSION: Patients with and without hypertension exhibit the same arousal response (as measured by BIS) to tracheal intubation despite the enhanced vasopressor response in hypertensive patients.
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