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Title: Do defects in ion channel glycosylation set the stage for lethal cardiac arrhythmias? Author: Fozzard HA, Kyle JW. Journal: Sci STKE; 2002 Apr 30; 2002(130):pe19. PubMed ID: 11983936. Abstract: Many ion channels are modified by the addition of carbohydrate residues. Fozzard and Kyle discuss evidence that sialic acid residues on glycosylated cardiac sodium and potassium channels may be important for preventing early after-depolarizations that can result in cardiac arrhythmias.[Abstract] [Full Text] [Related] [New Search]