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  • Title: [Activity of nucleolar organizers in the cells of erythroblastic islands in the bone marrow in various erythropoietic functional states].
    Author: Kurenkov EL, Kuznetsov ME, Sheviakov SA, Rassokhin AG.
    Journal: Vestn Ross Akad Med Nauk; 2002; (3):13-6. PubMed ID: 11989283.
    Abstract:
    Erythroblastic islands (EIs) of the bone marrow are the morpho-functional units of the erythron. The functional state of the cells of EIs of varying maturity was first studied by estimating the activity of nucleolar organizers in intact rats and in rats with acute blood loss or posttransfusion polycythemia by the modified method of J. Croker and P. Nar. The intact rats had the largest number of nucleoli and intranuclear argentum inclusions located within and outside the nucleoli in EIs of proliferating classes: Class 1 EIs and reconstructing EIs and the smallest number in involutional EIs. Blood loss was accompanied by the enhanced activity of nucleolar organizers in EI cells. In polycythemia, the activity of the organizers changed in a more complicated manner.
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