These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Specific B lymphocyte suppression by infectious bursal agent (Gumboro disease virus) in chickens.
    Author: Hudson L, Pattison M, Thantrey N.
    Journal: Eur J Immunol; 1975 Oct; 5(10):675-9. PubMed ID: 11993333.
    Abstract:
    Chickens infected experimentally with infectious bursal agent (IBA) during embryonation or early after hatching show a severe depression of bursa-dependent lymphoid components, and associated immune functions. Data presented here and elsewhere show that the degree of B cell suppression correlates with the time of infection. This would be compatible with a virus-induced block in B lymphocyte differentiation. Accordingly, the virus may be cytopathic for early (bursal) but not late (circulating) B lymphocytes or, more likely, the virus inactivates those non-lymphoid bursal cells mediating lymphocyte differentiation.
    [Abstract] [Full Text] [Related] [New Search]