These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Does nitric oxide modulate mitochondrial energy generation and apoptosis?
    Author: Moncada S, Erusalimsky JD.
    Journal: Nat Rev Mol Cell Biol; 2002 Mar; 3(3):214-20. PubMed ID: 11994742.
    Abstract:
    The physiological role of nitric oxide (NO) in the maintenance of vascular tone, in synaptic transmission and in cellular defence is now firmly established. Recent evidence indicates that NO can also affect mitochondrial function. Here, we review findings indicating that NO through its interaction with components of the electron-transport chain might function not only as a physiological regulator of cell respiration, but also to augment the generation of reactive oxygen species by mitochondria, and thereby trigger mechanisms of cell survival or death.
    [Abstract] [Full Text] [Related] [New Search]