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  • Title: Lysozyme in corneal ulcer.
    Author: Mehra KS, Singh R, Bhatia RP, Sen PC, Singh H.
    Journal: Ann Ophthalmol; 1975 Nov; 7(11):1470-2. PubMed ID: 1200558.
    Abstract:
    In the present experimental study the role of lysozyme drops in healing of corneal ulcer of staphylococcal origin (sensitive to chloramphenicol) was studied on 16 albino rabbits. In 8 rabbits, in one eye placibo drops (distilled water) and in the other eye lysozyme 1% were put 4 times daily. In the other 8 rabbits, in one eye chloramphenicol drops 0.4% and in the other eye chloramphenicol drops 0.4% + lysozyme drops 1% were instilled 4 times daily. It was observed that the rate of healing of corneal ulcer was much earlier in the eyes which had local instillation of chloramphenicol drops + lysozyme in comparison to the eyes which had only chloramphenicol drops, lysozyme drops, or distilled water.
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