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  • Title: The potential of flow-through optosensors in pharmaceutical analysis.
    Author: Molina Díaz A, Ruiz Medina A, Fernández de Córdova ML.
    Journal: J Pharm Biomed Anal; 2002 May 15; 28(3-4):399-419. PubMed ID: 12008119.
    Abstract:
    The fundamental principles of flow-through optosensors, together with the most significant procedures and alternatives developed in the applications of flow-through optosensors to pharmaceutical analysis are reviewed. The most frequently used solid sensing zones, flow-through cells, manifolds, regeneration step and types of detection are considered. Single parameter, biparameter, and multiparameter sensors developed are reviewed and their most relevant features presented. Finally, a critical comparison with other analytical methodologies/techniques is performed and the potential of flow-through optosensors in pharmaceutical analysis and their future trends discussed.
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