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  • Title: Antibodies to DNA in patients with rheumatoid arthritis and juvenile rheumatoid arthritis.
    Author: Bell C, Talal N, Schur PH.
    Journal: Arthritis Rheum; 1975; 18(6):535-40. PubMed ID: 1201105.
    Abstract:
    Antibodies to double-stranded DNA (DSDNA) were found in 18 patients with RA, in 5 patients with JRA, and in 5 patients with undiagnosed connective tissue disease. Five patients had clinical features consistent with both RA and SLE, 11 with only RA, and 5 with only JRA. Based on these observations, the presence of serum anti-DSDNA antibodies should not be used as a sole criterion in the diagnosis of SLE.
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