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  • Title: Giant cavernous haemangioma with Kasabach-Merritt syndrome: a case report and review.
    Author: Frevel T, Rabe H, Uckert F, Harms E.
    Journal: Eur J Pediatr; 2002 May; 161(5):243-6. PubMed ID: 12012216.
    Abstract:
    UNLABELLED: We report the case of a 4-month-old boy presenting with a giant cutaneous haemangioma complicated by Kasabach-Merritt syndrome (KMS) with severe thrombocytopenia. After poor response to corticosteroid therapy and subsequent treatment with interferon alpha-2a, radiotherapy led to tumour regression and resolution of the disseminated intravascular coagulopathy over a 14-month period of follow up. Whereas the various available treatment options are reviewed and discussed in this article, the therapy of choice should be chosen individually. CONCLUSION: to date prospective randomised and controlled trials are required to investigate the optimal management of patients with Kasabach-Merritt syndrome.
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