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  • Title: [Mathematical model of the cytokinetics of erythropoiesis in mouse bone marrow and spleen].
    Author: Znojil V, Vácha J.
    Journal: Biofizika; 1975; 20(4):661-8. PubMed ID: 1201301.
    Abstract:
    The described model approximates the function of the erythropoietic system of the mouse to the function of a self-renewed cellular system, describable in the terms of cell population kinetics. The model is based on a number of experimentally proved ideas of contemporary haematology and arises from the assumption that there exists mutual negative influence between the cellular populations of the bone marrow and spleen. Considering the erythropoietic system in the mouse to be composed of two relatively independent parts - the bone marrow and spleen - the described model differs from the attempts so far made on the mathematical modelling of erythropoiesis.
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