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  • Title: TEM-71, a novel plasmid-encoded, extended-spectrum beta-lactamase produced by a clinical isolate of Klebsiella pneumoniae.
    Author: Rasheed JK, Anderson GJ, Queenan AM, Biddle JW, Oliver A, Jacoby GA, Bush K, Tenover FC.
    Journal: Antimicrob Agents Chemother; 2002 Jun; 46(6):2000-3. PubMed ID: 12019125.
    Abstract:
    TEM-71, a novel extended-spectrum beta-lactamase from a Klebsiella pneumoniae clinical isolate, had an isoelectric point of 6.0 and a substrate profile showing preferential hydrolysis of cefotaxime over ceftazidime. It differed from TEM-1 by two substitutions, Gly238Ser and Glu240Lys, and was under the control of the strong P4 promoter.
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