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  • Title: Desmoplastic astrocytoma of infancy--a case report.
    Author: Kandalkar B, Shah V, Shet T.
    Journal: Indian J Pathol Microbiol; 2001 Jul; 44(3):329-32. PubMed ID: 12024924.
    Abstract:
    Desmoplastic cerebral astrocytoma of infancy (DCAI) is a rare tumor which shows spindle cells embedded in an extremely desmoplastic stroma. We describe a case of DCAI seen in the frontoparietal region of brain in a three-month-old infant. Microscopically classic histology of DCAI was seen. On immunohistochemistty the tumor showed strong Vimentin, S-100 and Glial Fibrillary Acidic Protein (GFAP) positivity. The brain adjacent to the tumor-showed multi-cystic transformation and the tumor formed a solid area in the wall of this cystic structure. This adjacent brain showed mild disarray of architecture and gliosis. Three months after surgery this infant was alive and well.
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