These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Immunocytochemical localization of growth hormone-releasing hormone-like peptide in the brain of the tiger frog, Rana tigrina.
    Author: Bhargava S, Risbud MV, Prasad Rao PD.
    Journal: Gen Comp Endocrinol; 2002 Apr; 126(2):200-12. PubMed ID: 12030776.
    Abstract:
    Using antisera directed against carp growth hormone-releasing hormone (cGHRH), we found more extensive brain distribution of GHRH-like immunoreactive (ir) neurons in the tiger frog, Rana tigrina, than reported in previous studies, which employed mammalian GHRH antibodies. In the telencephalon, GHRH-ir perikarya were present in the pallium dorsale, pallium laterale (pars dorsalis and pars ventralis), pallium mediale, nucleus entopeduncularis, amygdala pars medialis, and in the ventral portion of the lateral preoptic area. Most GHRH somata were present in the nucleus infundibularis ventralis located around the third ventricle, extending from the region posterior to the optic chiasma to the caudal end of infundibulum. In the thalamic region, GHRH-ir perikarya occurred in the area ventrolateralis thalami, the nuclei posterocentralis thalami, and the posterolateralis thalami. The ir cell bodies in the nucleus posteroventralis tegmenti mesencephali represented the caudal-most brain GHRH perikarya. Extensive GHRH-ir fibers occurred around the nonreactive cells in the ventral preoptic area and ventral area of the infundibulum. GHRH-ir fibers were present in the outer layers of the median eminence, but not in the neural lobe or pars distalis of the pituitary gland. This wider neuroanatomical distribution of GHRH-like peptide in the brain of R. tigrina should, provide the basis for future studies to establish the exact role of GHRH-like peptides in anuran brain.
    [Abstract] [Full Text] [Related] [New Search]