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  • Title: [Biosynthesis of proteins and ribonucleic acids in red and white rat skeletal muscles].
    Author: Kazarian VA, Goncharova LA, Zelenina IA, Rapoport ZA.
    Journal: Biokhimiia; 1975; 40(2):290-6. PubMed ID: 1203349.
    Abstract:
    Protein biosynthesis is studied in red and white rat shank muscles in vitro. It is found that the incorporation rate of 14C-lysine in red muscle was 2-fold higher than that in white muscle. The difference in the lysine incorporation rate into muscle proteins studied increased with the increase of lysine molar concentration in the incubation medium, which was probably due to a selective protein synthesis activation in the red muscle. A higher level of 14C-lysine incorporation in red muscle proteins was found under similar uptake of the labelled amino acid in both red and white muscles. RNA synthesis rate was the same in both muscles and its inhibition with actinomycin D did not affect the ratio of protein synthesis rates in red and white muscles.
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