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  • Title: Studies on the psychopharmacological activities of Rumex nepalensis Spreng. root extract in rats and mice.
    Author: Ghosh L, Arunachalam G, Murugesan T, Pal M, Saha BP.
    Journal: Phytomedicine; 2002 Apr; 9(3):202-6. PubMed ID: 12046859.
    Abstract:
    The methanol extract of Rumex nepalensis Spreng. (Family - Polygonaceae) was assessed for different psychopharmacological activities in rats and mice by evaluation of general behaviour, exploratory behaviour, muscle relaxant activity and phenobarbitone sodium-induced sleeping time. The extract at doses 200 mg/kg and above exhibited a reduction in spontaneous activity (general behavioural profile), a decrease in exploratory behavioural pattern in the Y-maze and Head-dip tests, a reduction in muscle relaxant activity in rotarod, 30 degrees inclined screen and traction tests, and also potentiated phenobarbitone sodium-induced sleeping time.
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