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  • Title: [Participation of the cardiac sympathetic innervation in the occurrence of vagotomic and atropine tachycardia in anesthetized dogs].
    Author: Nikol'skaia MG, Samonina GE, Udel'nov MG.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1975 Oct; 61(10):1449-53. PubMed ID: 1204856.
    Abstract:
    The sympathetic nervous system's role in the post-vagotomy and atropin-induced tachycardia was studied in anesthetized dogs. Bilateral vagotomy was followed by 166% tachycardia while on exclusion of the heart sympathetic innervation (inderal or novocain injections into the right stellate ganglion) the bilateral vagotomy was accompanied by a considerably lesser tachycardia (33%). The i.v. atropine administration increased the heart rate by 177% whereas in the presence of inderal it increased the heart rate by 77% only. Thereupon, the post-vagotomy or atropin-induced tachycardia in anesthetized dogs was to a considerable extent associated with activation of the sympatho-adrenal system.
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