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  • Title: Central nervous system pharmacology of propranolol.
    Author: Iyer KS, Govindankutty A, Radha M.
    Journal: Indian J Physiol Pharmacol; 1975; 19(3):152-6. PubMed ID: 1205559.
    Abstract:
    In rats, propranolol potentiated alcohol and pentobarbitone hypnosis, but not barbital sleeping time, indicating enzyme inhibition as a possible mechanism of potentiation. Propranolol showed anticonvulsant effect on normal and reserpine treated rats by MES test, but showed dose related lowering of MET. Probable mechanisms are discussed.
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