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  • Title: A case of azoospermia in a bull carrying a Y-autosome reciprocal translocation.
    Author: Iannuzzi L, Molteni L, Di Meo GP, De Giovanni A, Perucatti A, Succi G, Incarnato D, Eggen A, Cribiu EP.
    Journal: Cytogenet Cell Genet; 2001; 95(3-4):225-7. PubMed ID: 12063403.
    Abstract:
    During normal cytogenetic investigations on the Chianina cattle (BTA) breed, a normal looking young bull was found to carry an abnormal Y chromosome which was a product of a reciprocal translocation between chromosomes Y and 9. This was revealed by both CBA- and RBG-banding techniques and was clearly confirmed by FISH-mapping analysis with IDVGA50 (which paints the complete Yq arm in a normal Y), as well as with AMD1, CGA, IGF2R (mapping to BTA9q16, BTA9q22 and BTA9q27-->q28, respectively) and SRY (mapping to normal BTAYq23). Analysis on sperm from four different samples revealed azoospermia in the carrier, indicating that the rcp(Y;9) induces sterility in the bull.
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