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  • Title: Treatment of scleroderma skin ulcers using becaplermin gel and hydrocolloid membrane.
    Author: Yoon J, Giacopelli J, Granoff D, Kobayashi W.
    Journal: J Am Podiatr Med Assoc; 2002 Jun; 92(6):350-4. PubMed ID: 12070235.
    Abstract:
    Skin ulcers can be very painful and detrimental in patients with systemic sclerosis, or systemic scleroderma. A brief review of scleroderma skin ulcers is presented, as well as a case study that demonstrates the effectiveness of becaplermin gel supplemented by oral immunosuppressive agents in the treatment of ulcers resulting from systemic sclerosis. The time to healing (approximately 3 months) was comparable to that associated with the oral agents and surgical interventions specifically designed to help heal scleroderma ulcers. Except for incisional biopsy, no surgical procedures were performed.
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