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  • Title: Sister chromatid exchanges--a sensitive assay of agents damaging human chromosomes.
    Author: Solomon E, Bobrow M.
    Journal: Mutat Res; 1975 Nov; 30(2):273-8. PubMed ID: 1207711.
    Abstract:
    Sister chromatid exchange frequencies in human lymphocyte chromosomes are greatly increased by alkylating agents, but ionizing radiation has little if any such effect. Scoring these exchanges may provide a useful technique for exploring the mechanisms of chromosome breakage and repair.
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