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  • Title: [The degeneration and regeneration of skeletal muscle after tenotomy].
    Author: Tang X, Liu B, Gu X.
    Journal: Hua Xi Kou Qiang Yi Xue Za Zhi; 1998 Feb; 16(1):15-6, 19. PubMed ID: 12078172.
    Abstract:
    In order to investigate the degeneration and regeneration of skeletal muscle fiber after tenotomy, the tenotomy were carried out on gastrocnemius muscles in 15 adult BALB/C mice. The tenotomized muscles were removed on 1, 2 and 4 weeks postoperatively. Specimens were processed for histological study with light microscope and TEM, and skeletal muscle specific protein expression analysis with myoactin (MA) and myoglobin (MG) immunohistochemical staining. The results showed that the regenerating muscle cells and the degenerating muscle fibre coexisted in tenotomized muscle. The internal structure and histochemical pattern of muscle fiber changed after tenotomy. The regenerating muscle cells fused with degenerating fibres.
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