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  • Title: [Genetic analysis of deltamethrin resistance in Culex pipiens pallens].
    Author: Zhu C, Li Y, Sun L, Li J, Gao X, Ye B.
    Journal: Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi; 1998; 16(1):21-4. PubMed ID: 12078202.
    Abstract:
    AIM: To analyse the genetic character of deltamethrin resistant laboratory strain (resistant factor being 518) of Cx. pipiens pallens. METHODS: Genetic studies were made of deltamethrin-susceptible and-resistant strains of Cx. pipiens pallens with LC-P curve constructed from the response of fourth instar larvae to deltamethrin treatment, and the resistance mechanisms were analysed with synergetic tests in PB, DEF and TPP. RESULTS: The resistant factors of F1 generation from cross and reciprocal cross are respectively 154.8 and 159.2; the LC-P curve of F1 generation gets near to that of resistant parents, D = 0.625; there exist no obvious platform in 50% mortality of BC generation and 25% and 75% mortality of F2 generation, and there are larger differences between the determining curve and theoretical curve in both BC and F2 generations, P < 0.01; the synergetic ratios of PB, DEF and TPP are 27.13, 1.22 and 1.05. CONCLUSION: Deltamethrin resistance of Cx. pipiens pallens is controlled by two or more autosomal genes, and the main gene involved is incompletely dominant; multi-functional oxidase is mainly responsible for the resistance.
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