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Title: Progesterone facilitation of sexual receptivity in rats with neural implantation of estrogen. Author: Lisk RD, Barfield MA. Journal: Neuroendocrinology; 1975; 19(1):28-35. PubMed ID: 1207871. Abstract: The neural substrate for estrogen (E) AND E plus progesterone (P)-induced sexual receptivity was examined in 3 classes of adult rats: (1) adult females ovariectomized for 11 days, and (2) females and (3) males gonadectomized on the day of birth. E responses were found only after implantation in the preoptic or medial hypothalamus; adult females had the largest fraction of responders. The addition of P significantly increased the fraction of adult and neonatally ovariectomized females responding when E implantation was made throughout the hypothalamus from preoptic to mammillary bodies. No E-P synergistic effects were seen in the day-1 gonadectomized males. E-P synergistic effects were found in the amygdala of the adult ovariectomized females. However, midbrain implants of E were ineffective for facilitating E-P-induced receptivity in the 3 classes of animals studied.[Abstract] [Full Text] [Related] [New Search]