These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Thrombosis induced by homocysteine does not depend on platelet aggregation or heparin cofactor's antithrombin activity].
    Author: Zhang L, Zhang G.
    Journal: Hunan Yi Ke Da Xue Xue Bao; 1999; 24(4):309-12, 340. PubMed ID: 12080632.
    Abstract:
    OBJECTIVES: To partly elucidate the relationship between homocysteine(Hcy) and thrombosis, we observed Hcy's effects on platelet aggregation and antithrombin activity of heparin cofactor in vitro. METHODS: Platelet aggregation assay and chromogenic assay were used in this research. RESULTS: Homocysteine had no effects on platelet aggregation induced by ADP and thrombin or heparin cofactor's antithrombin activity in vitro (P > 0.05). CONCLUSION: There is no correlation between Hcy and the "ADP passway" of platelet aggregation. Thrombosis induced by Hcy does not depend on heparin cofactor's antithrombin activity either.
    [Abstract] [Full Text] [Related] [New Search]