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  • Title: [Relationship between hypotension during hemodialysis and autonomic dysfunction in diabetic hemodialysis patients].
    Author: Ning J, Sun M, Ikeda T.
    Journal: Hunan Yi Ke Da Xue Xue Bao; 1999; 24(6):572-4. PubMed ID: 12080725.
    Abstract:
    OBJECTIVE: To observe the change of autonomic nerve function in diabetes mellitus(DM) patients who receive hemodialysis and to explore the relationship between this change and hypotension during hemodialysis. METHODS: Twenty-five DM patients and 40 chronic glomerulonephritis(CGN) patients who received hemodialysis were checked. We tested their coefficient of variation R-R(CVR-R) in ECG, difference of systolic blood pressure between lying and standing positions, and serum parathyroid hormone(PTH); monitored the decrease of blood pressure during hemodialysis. RESULTS: The rate(80.0%) of autonomic dysfunction(AD) in DM group is significantly higher than that(57.5%, P < 0.05) in CGN group. The rate(37.2%) of hypotension in those who had AD was significantly higher than that(18.2%, P < 0.05) in those who had normal autonomic nerve function during hemodialysis. No significant difference was found in PTH between each group. CONCLUSION: DM patients who receive hemodialysis are often complicated with AD, which is one of the reasons that causes hypotension during hemodialysis.
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