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  • Title: [Effects of basic fibroblast growth factor on the healing of cutaneous chronic wounds].
    Author: Fu XB, Guo ZR, Sheng ZY.
    Journal: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 1999 Sep; 13(5):270-2. PubMed ID: 12080816.
    Abstract:
    OBJECTIVE: To observe the effects of basic fibroblast growth factor(bFGF) on the healing of cutaneous chronic wounds. METHODS: Twenty-eight cases with thirty-three wounds from trauma, diabetes, pressure and radiation injuries were locally treated with bFGF in a dosage of 150 U/cm2 wounds. The healing time of wounds was used to evaluate the treatment results. RESULTS: The healing time in all of chronic wounds were accelerated. All wounds from trauma, diabetes and pressure were healed within 4 weeks and another 2 wounds from radiation injuries were healed over 4 weeks. The healing rate within 4 weeks was 93.9%. CONCLUSION: The results indicate that bFGF can be used as a promoter to accelerate the healing of chronic wounds in clinic.
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