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  • Title: Cardiovascular and renal responses to mental challenge in highly and moderately active males with a family history of hypertension.
    Author: Hamer M, Boutcher Y, Boutcher SH.
    Journal: J Hum Hypertens; 2002 May; 16(5):319-26. PubMed ID: 12082492.
    Abstract:
    The objective of this study was to compare FBF and renal responses to mental challenge in highly and moderately active males with a family history of hypertension. Normotensive, healthy males with a family history of hypertension (n = 18) were recruited into moderately active and highly active groups. Cardiovascular, FBF, and renal responses to a 10-min Stroop mental challenge were measured. Urine was analysed for levels of sodium and potassium pre and post stressor as an indicant of renal blood flow. The results were that the moderately active males demonstrated a significantly higher level of FBF reactivity to mental challenge compared with that of the highly active. Heart rate change and FBF change during the stressor were positively correlated (r = 0.75, P < 0.01). Both groups, however, demonstrated a similar pattern of sodium excretion to mental challenge. These findings suggest that physical activity level is associated with FBF reactivity but not renal reactivity to mental challenge in offspring hypertensives. That sodium excretion was no different post-stressor in the moderately active group suggests that the exaggerated forearm vasodilatation response was not due to renal vasoconstriction.
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