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Pubmed for Handhelds

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  • Title: (Re-)Engineering tumor cell-selective replicating adenoviruses: a step in the right direction toward systemic therapy for metastatic disease.
    Author: Dubensky TW.
    Journal: Cancer Cell; 2002 May; 1(4):307-9. PubMed ID: 12086842.
    Abstract:
    An approach combining redundant controls to restrict the productive infection of adenoviruses to cells that are disrupted in the pRb pathway-a hallmark of human cancer-has resulted in a novel oncolytic virus that may be well suited for systemic administration to treat metastatic disease.
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