These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Isolation of a new mycalolide from the marine sponge Mycale izuensis.
    Author: Phuwapraisirisan P, Matsunaga S, van Soest RW, Fusetani N.
    Journal: J Nat Prod; 2002 Jun; 65(6):942-3. PubMed ID: 12088446.
    Abstract:
    Bioassay-directed fractionation of the lipophilic extract of the marine sponge Mycale izuensis led to the isolation of cytotoxic mycalolides including a new compound, 30,32-dihydroxymycalolide A (1). Its structure including absolute stereochemistry was deduced by spectroscopic and chemical methods. Compound 1 was cytotoxic against HeLa cells with an IC(50) value of 2.6 ng/mL.
    [Abstract] [Full Text] [Related] [New Search]