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  • Title: Nationwide survey of in vitro activities of itraconazole and voriconazole against clinical Aspergillus fumigatus isolates cultured between 1945 and 1998.
    Author: Verweij PE, Te Dorsthorst DT, Rijs AJ, De Vries-Hospers HG, Meis JF.
    Journal: J Clin Microbiol; 2002 Jul; 40(7):2648-50. PubMed ID: 12089298.
    Abstract:
    The isolates in a collection of 170 Aspergillus fumigatus isolates recovered from 114 patients and 21 different medical centers in The Netherlands over a period of 53 years were tested for the presence of resistance to itraconazole and voriconazole according to the guidelines of NCCLS document M38-P and by the E-test. Three isolates were highly resistant to itraconazole, and voriconazole MICs were low for all isolates.
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