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  • Title: Characteristics of an ovine herpesvirus associated with pulmonary adenomatosis (jaagsiekte) in sheep.
    Author: de Villiers EM, Els HJ, Verwoerd DW.
    Journal: S Afr J Med Sci; 1975; 40(4):165-75. PubMed ID: 1209391.
    Abstract:
    The isolation of an ovine herpesvirus from a cell culture of an adenomatous sheep lung is reported, confirming previous observations of a possible association of a herpesvirus with this tumour. Some growth properties and morphological characteristics of the virus are described, as well as serological data supporting a possible relationship between tumour and virus. Attempts to produce jaagsiekte by intratracheal injection of virus into lambs were unsuccessful, suggesting that a second factor may be involved inthe oncogenic process possibly similar to that proposed for the well-known EBV-Burkitt's lymphoma system.
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