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  • Title: [The effect of excess amounts of qualitatively differing fats on liver lipogenesis].
    Author: Liapkov BG, Markelova VF, Rudich LV.
    Journal: Vopr Pitan; 1975; (5):49-52. PubMed ID: 1210202.
    Abstract:
    Tests conducted with rats receiving for 30 days isocaloric with control rations containing an elevated amount of animal or vegetable fats (lard, sunflower oil) demonstrated that the influence of the said fat-rich rations on the lipogenesis in the liver presents certain peculiarities that find their expression in a different intensity with which the components of the carbohydrate, fat and interstitial metabolism behave in reactions of the lipids synthesis. Both rations tend to slightly bring down the rate of the endogenous fatty acids formation but contribute to a more intensive synthesis of glycerides and fatty acids cholesterol ethers. The vegetable oils, where are prevalent polysaturated fatty acids, provoke an accelerated utilization of carbohydrates in the synthesis of the glycerin structure of glycerides and phospholipids, as well as of the palimitic acid metabolites and the C-2 fragments in the liver cholesterol synthesis.
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