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  • Title: [The effect of phenamine and caffeine on caudate inhibition of conditioned reflex avoidance reactions in cats].
    Author: Arushanian EB, Karpov VN.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1975; 25(4):744-51. PubMed ID: 1210720.
    Abstract:
    In cats with a preliminarily learned conditioned avoidance reaction, stimulation of the caudate nucleus inhibited behavioral response by lengthening its latency and reducing the number of conditioned reactions. Intensity of the inhibitory effect did not substantially depend on the localization of electrodes in the head or body of the nucleus and weakened within a few experimental days. D,1-amphetamine (0.5 to 4 mg/kg) and caffeine (10 to 10 mg/kg) suppressed the caudate inhibition, but the action of the drugs was manifested in different ways. The influence of large doses of d,1-amphetamine was characterized by a serious disturbance of behaviour and caudate inhibition of conditioned responses.
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