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  • Title: Anticonvulsant and sedative effects of Salvadora persica L. stem extracts.
    Author: Monforte MT, Trovato A, Rossitto A, Forestieri AM, D'Aquino A, Miceli N, Galati EM.
    Journal: Phytother Res; 2002 Jun; 16(4):395-7. PubMed ID: 12112302.
    Abstract:
    The effect of Salvadora persica L. stem extracts on the potentiation of sodium pentobarbital activity and on generalized tonic-clonic seizure produced by pentylenetetrazol (PTZ) on the rat is reported. The extracts of Salvadora persica L. extended sleeping-time and decreased induction-time induced by sodium pentobarbital; in addition it showed protection against pentylenetetrazol-induced convulsion by increasing the latency period and diminishing the death rate.
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