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  • Title: Human platelet aggregation inhibitors from thyme (Thymus vulgaris L.).
    Author: Okazaki K, Kawazoe K, Takaishi Y.
    Journal: Phytother Res; 2002 Jun; 16(4):398-9. PubMed ID: 12112303.
    Abstract:
    Two antiaggregant compounds, thymol (compound 1) and 3,4,3',4'-tetrahydroxy-5,5'-diisopropyl-2,2'-dimethylbiphenyl (compound 2) were isolated from the leaves of thyme (Thymus vulgaris L.). The structures were determined by (1)H-, (13)C-NMR and mass spectra (MS) studies. These compounds inhibited platelet aggregation induced by collagen, ADP, arachidonic acid (AA) and thrombin except that compound 2 did not inhibit platelet aggregation induced by thrombin.
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