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  • Title: Inhibition of ADP-triggered blood platelet aggregation by diadenosine polyphosphate analogues.
    Author: Walkowiak B, Baraniak J, Cierniewski CS, Stec W.
    Journal: Bioorg Med Chem Lett; 2002 Aug 05; 12(15):1959-62. PubMed ID: 12113818.
    Abstract:
    The synthesis and biological evaluation of new diadenosine polyphosphate analogues on blood platelet aggregation are reported. The most active are compounds with a sulfur atom replacing one or both non-bridging oxygens at phosphorus bound to adenosyl residues and hydroxymethyl groups of bis(hydroxymethyl)phosphinic acid.
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