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  • Title: Atractyligenine chemistry, Part VI: Synthesis and biological activities of atractyligenine derivatives.
    Author: Camarda L, Di Stefano V, Schillaci D.
    Journal: Pharmazie; 2002 Jun; 57(6):374-6. PubMed ID: 12116872.
    Abstract:
    Derivatives of atractyligenine, the aglycone of atractyloside, were tested in vitro for their antimicrobial and antiproliferative activity against K-562 (human chronic myelogeneous leukemia), HL-60 (human leukemia) and MCF-7 (human breast adenocarcinoma) cell lines. The most active compound showed IC50 values in the range 0.8-6.9 microM.
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