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  • Title: Hedgehog signalling: pulling apart patched and smoothened.
    Author: Stark DR.
    Journal: Curr Biol; 2002 Jun 25; 12(12):R437-9. PubMed ID: 12123598.
    Abstract:
    Two integral membrane proteins, Patched and Smoothened, were for a long time thought to comprise a preformed receptor complex for secreted Hedgehog signalling proteins. Recent analyses of the subcellular distribution of these proteins argue strongly against this simple model.
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