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  • Title: The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class.
    Author: Sciotti RJ, Pliushchev M, Wiedeman PE, Balli D, Flamm R, Nilius AM, Marsh K, Stolarik D, Jolly R, Ulrich R, Djuric SW.
    Journal: Bioorg Med Chem Lett; 2002 Aug 19; 12(16):2121-3. PubMed ID: 12127518.
    Abstract:
    A novel series of antimicrobials of the oxazolidinone class is disclosed. These compounds are characterized relative to previously described analogues by a 'halostilbene-derived' pharmacophore and demonstrate enhanced antimicrobial activity against key Gram-positive pathogens when compared to Linezolid.
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