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  • Title: Keratopathy from congenital syphilis.
    Author: Hariprasad SM, Moon SJ, Allen RC, Wilhelmus KR.
    Journal: Cornea; 2002 Aug; 21(6):608-9. PubMed ID: 12131041.
    Abstract:
    PURPOSE: Therapeutic decision-making in syphilitic corneal disease is discussed after seeing a patient with keratopathy from congenital syphilis. METHODS: Case report and review of the literature. RESULTS: Laboratory evaluation of our patient revealed a nonreactive serum rapid plasma reagin (RPR) test and a positive microhemagglutination assay-Treponema pallidum (MHA-TP) test. CONCLUSION: Any patient with residual interstitial keratopathy, especially if bilateral, should be suspected to have congenital syphilis if the patient or parents were ever treated for a sexually transmitted disease, if stigmata of congenital syphilis are present, or if childhood ocular inflammation occurred.
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