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  • Title: [The role of the caudate nucleus in the development of convulsive discharges].
    Author: Avakian RM, Arushanian EB.
    Journal: Fiziol Zh SSSR Im I M Sechenova; 1975 Apr; 61(4):480-7. PubMed ID: 1213172.
    Abstract:
    A single or rhythmical (1-3/sec) stimulation of the caudate nucleus in unrestrained rats facilitated formation of slow negative waves and the spike-wave complexes in the EEG of the sensory-motor cortex and contralateral neostriatum, as well as development of behavioral disturbances due to subseisure doses of pentylentetrazol. During the low-frequency stimulation of the caudate nucleus or after its cessation, when giving the convulsant drug, regular potentials of the spike-wave type or a general seizure may occur. The caudate nucleus is supposed to be able to participate in the petit mal seizure mechanisms because of its syndhronizing influences on the cortex.
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