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  • Title: [Use of propofol for carotid endarterectomy: its effect on parameters of intraoperative monitoring and clinical outcomes].
    Author: Nakagawa I, Hamada H, Uesugi F, Sakai A, Katsuya C, Matsubara Y.
    Journal: Masui; 2002 Jun; 51(6):605-10. PubMed ID: 12134648.
    Abstract:
    In order to evaluate the effects of propofol on neurologic outcomes of patients for carotid endarterectomy (CEA), intraoperative monitoring and postoperative complications were evaluated. Fifty two CEA cases were divided into two groups according to the method of anesthesia; group P (+) using propofol (n = 26), and group P (-) without propofol (n = 26). During cross-clamping of the internal carotid artery, oxygen saturation of internal jugular vein (SjO2) and somatosensory evoked potentials(SEP) were monitored continuously on the operated side. Moreover, the patients with postoperative neurological complications were examined for each parameter. There were no significant differences between the two groups in %SjO2, %SEP and number of cases with neurologic deficits. In the patients with poor outcomes, the value of stump pressure (SP) was significantly lower. We conclude that propofol had no significant effect against neurological complications in CEA patients, and SP monitoring was effective for evaluation of the clinical outcome in CEA patients.
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