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  • Title: Two cases of polymorphic ventricular tachycardia induced by the administration of verapamil against paroxysmal supraventricular tachycardia.
    Author: Shiraishi H, Ishibashi K, Urao N, Hyogo M, Tsukamoto M, Keira N, Hirasaki S, Seo Y, Shirayama T, Nakagawa M.
    Journal: Intern Med; 2002 Jun; 41(6):445-8. PubMed ID: 12135176.
    Abstract:
    Verapamil is widely used for the termination of paroxysmal supraventricular tachycardia (PSVT) with little proarrhythmic effect. We describe two cases of PSVT that changed to non-sustained polymorphic ventricular tachycardia after administration of verapamil. Electrophysiological study revealed atrioventricular nodal reentrant tachycardia in the first case, and atrioventricular reentrant tachycardia due to a concealed left lateral accessory pathway in the second case. Catecholamine-induced automaticity was one of the possible mechanisms of VT in the first case, but the mechanism is unknown in the second case.
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