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  • Title: [Directed biosynthesis of proteolytic enzymes in Actinomyces thermovulgaris].
    Author: Vygornykh SN, Egorov NS.
    Journal: Mikrobiologiia; 1975; 44(6):993-8. PubMed ID: 1214619.
    Abstract:
    The biosynthesis of proteolytic enzymes in the thermophilic culture of Actinomyces thermovulgaris, strain T-54, was directed by changing the composition of the medium and the temperature of cultivation. A temperature of 40 degrees C is optimal for the growth and production of neutral and alkaline proteases. The maximum activity of acid proteases was found during the growth on a complex medium at 30 degrees C. An increase of temperature to 50 degrees C during the cultivation of the microorganism on a chemically defined medium resulted in its secondary growth and a sharp rise in the activity of alkaline and neutral proteases.
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